PD Dr. Carlos Ros

Journal Article

Bieri, Jan; Suter, Corinne; Caliaro, Oliver; Bartetzko, Seraina; Bircher, Cornelia; Ros, Carlos (2024). Globoside Is an Essential Intracellular Factor Required for Parvovirus B19 Endosomal Escape. Cells, 13(15) MDPI 10.3390/cells13151254

Suter, Corinne; Colakovic, Minela; Bieri, Jan; Gultom, Mitra; Dijkman, Ronald; Ros, Carlos (2023). Globoside and the mucosal pH mediate parvovirus B19 entry through the epithelial barrier. PLoS pathogens, 19(5), e1011402. Public Library of Science 10.1371/journal.ppat.1011402

Leisi, Remo; Rostami, Iman; Laughhunn, Andrew; Bieri, Jan; Roth, Nathan J; Widmer, Eleonora; Ros, Carlos (2022). Visualizing protein fouling and its impact on parvovirus retention within distinct filter membrane morphologies. Journal of membrane science, 659, p. 120791. Elsevier 10.1016/j.memsci.2022.120791

Bircher, Cornelia; Bieri, Jan; Assaraf, Ruben; Leisi, Remo; Ros, Carlos (2022). A Conserved Receptor-Binding Domain in the VP1u of Primate Erythroparvoviruses Determines the Marked Tropism for Erythroid Cells. Viruses, 14(2) 10.3390/v14020420

Leisi, Remo; Wolfisberg, Raphael; Nowak, Thomas; Caliaro, Oliver; Hemmerle, Andreas; Roth, Nathan J.; Ros, Carlos (2021). Impact of the isoelectric point of model parvoviruses on viral retention in anion‐exchange chromatography. Biotechnology and bioengineering, 118(1), pp. 116-129. Wiley 10.1002/bit.27555

Leisi, Remo; Widmer, Eleonora; Gooch, Barry; Roth, Nathan J.; Ros, Carlos (2021). Mechanistic Insights into Flow-Dependent Virus Retention in Different Nanofilter Membranes. Journal of membrane science, 636, p. 119548. Elsevier 10.1016/j.memsci.2021.119548

Meier, Anita Felicitas; Tobler, Kurt; Leisi, Remo; Lkharrazi, Anouk; Ros, Carlos; Fraefel, Cornel (2021). Herpes simplex virus co-infection facilitates rolling circle replication of the adeno-associated virus genome. PLoS pathogens, 17(6), e1009638. Public Library of Science 10.1371/journal.ppat.1009638

Bieri, Jan; Leisi, Remo; Bircher, Cornelia; Ros, Carlos (2021). Human parvovirus B19 interacts with globoside under acidic conditions as an essential step in endocytic trafficking. PLoS pathogens, 17(4), e1009434. Public Library of Science 10.1371/journal.ppat.1009434

Ros, Carlos; Bieri, Jan; Leisi, Remo (2020). The VP1u of Human Parvovirus B19: A Multifunctional Capsid Protein with Biotechnological Applications. Viruses, 12(12), p. 1463. MDPI 10.3390/v12121463

Leisi, Remo; Bieri, Jan; Roth, Nathan J.; Ros, Carlos (2020). Determination of parvovirus retention profiles in virus filter membranes using laser scanning microscopy. Journal of membrane science, 603, p. 118012. Elsevier 10.1016/j.memsci.2020.118012

Bieri, Jan; Ros, Carlos (2019). Globoside Is Dispensable for Parvovirus B19 Entry but Essential at a Postentry Step for Productive Infection. Journal of virology, 93(20) American Society for Microbiology 10.1128/JVI.00972-19

Bochud, Maëlle; Schäfer, Wolfram; Roth, Nathan J.; Ros, Carlos (2019). Characterization of a quasi-enveloped, fast replicating hepevirus from fish and its use as hepatitis E virus surrogate. Journal of virological methods, 263, pp. 111-119. Elsevier 10.1016/j.jviromet.2018.11.002

Caliaro, Oliver; Marti, Andrea; Ruprecht, Nico; Leisi, Remo; Subramanian, Suriyasri; Hafenstein, Susan; Ros, Carlos (2019). Parvovirus B19 Uncoating Occurs in the Cytoplasm without Capsid Disassembly and It Is Facilitated by Depletion of Capsid-Associated Divalent Cations. Viruses, 11(5), p. 430. MDPI 10.3390/v11050430

Ros, Carlos; Bayat, Nooshin; Wolfisberg, Raphael; Almendral, José M (2017). Protoparvovirus Cell Entry. Viruses, 9(11) MDPI 10.3390/v9110313

von Nordheim, Marcus; Boinay, Michel Thomas; Leisi, Remo; Kempf, Christoph; Ros, Carlos (2016). Cutthroat Trout Virus-Towards a Virus Model to Support Hepatitis E Research. Viruses, 8(10), p. 289. MDPI 10.3390/v8100289

Leisi, Remo; von Nordheim, Marcus; Ros, Carlos; Kempf, Christoph (2016). The VP1u Receptor Restricts Parvovirus B19 Uptake to Permissive Erythroid Cells. Viruses, 8(10), p. 265. MDPI 10.3390/v8100265

Wolfisberg, Raphael; Kempf, Christoph; Ros, Carlos (2016). Late Maturation Steps Preceding Selective Nuclear Export and Egress of Progeny Parvovirus. Journal of virology, 90(11), pp. 5462-5474. American Society for Microbiology 10.1128/JVI.02967-15

Leisi, Remo; Di Tommaso, Chiarina; Kempf, Christoph; Ros, Carlos (2016). The Receptor-Binding Domain in the VP1u Region of Parvovirus B19. Viruses, 8(3), p. 61. MDPI 10.3390/v8030061

Leisi, Remo; von Nordheim, Marcus; Kempf, Christoph; Ros, Carlos (2015). Specific Targeting of Proerythroblasts and Erythroleukemic Cells by the VP1u Region of Parvovirus B19. Bioconjugate chemistry, 26(9), pp. 1923-1930. American Chemical Society 10.1021/acs.bioconjchem.5b00321

Leisi, Remo; Ruprecht, Nico; Kempf, Christoph; Ros, Carlos (2013). Parvovirus B19 uptake is a highly selective process controlled by VP1u, a novel determinant of viral tropism. Journal of virology, 87(24), pp. 13161-13167. American Society for Microbiology 10.1128/JVI.02548-13

Wolfisberg, Raphael; Ruprecht, Nico; Kempf, Christoph; Ros, Carlos (2013). Impaired genome encapsidation restricts the in vitro propagation of human parvovirus B19. Journal of virological methods, 193(1), pp. 215-225. Elsevier 10.1016/j.jviromet.2013.06.003

Quattrocchi, Silva; Ruprecht, Nico; Bönsch, Claudia; Bieli, Sven; Zürcher, Christoph; Boller, Klaus; Kempf, Christoph; Ros, Carlos (2012). Characterization of the early steps of human parvovirus B19 infection. Journal of virology, 86(17), pp. 9274-9284. Baltimore: American Society for Microbiology 10.1128/JVI.01004-12

Bönsch, Claudia; Zuercher, Christoph; Lieby, Patricia; Kempf, Christoph; Ros, Carlos (2010). The globoside receptor triggers structural changes in the B19V capsid that facilitate virus internalization. Journal of virology, 84(22), pp. 11737-11746. Baltimore: American Society for Microbiology 10.1128/JVI.01143-10

Bönsch, Claudia; Kempf, Christoph; Müller, Ivo; Manning, Laurens; Laman, Moses; Davis, Timothy M.E.; Ros, Carlos (2010). Chloroquine and its derivatives exacerbate B19V-associated anemia by promoting viral replication. PLoS neglected tropical diseases, 4(4), e669. San Francisco, Calif.: Public Library of Science 10.1371/journal.pntd.0000669

Boensch, Claudia; Kempf, Christoph; Ros, Carlos (2008). Interaction of parvovirus B19 with human erythrocytes alters virus structure and cell membrane integrity. Journal of virology, 82(23), pp. 11784-11791. Baltimore: American Society for Microbiology 10.1128/JVI.01399-08

Mani, Bernhard; Gerber, Marco; Lieby, Patricia; Boschetti, Nicola; Kempf, Christoph; Ros, Carlos (2007). Molecular mechanism underlying B19 virus inactivation and comparison to other parvoviruses. Transfusion, 47(10), pp. 1765-1774. Malden, Mass.: Wiley-Blackwell 10.1111/j.1537-2995.2007.01393.x

Ros, Carlos; Baltzer, Claudia; Mani, Bernhard; Kempf, Christoph (2006). Parvovirus uncoating in vitro reveals a mechanism of DNA release without capsid disassembly and striking differences in encapsidated DNA stability. Virology, 345(1), pp. 137-147. New York, N.Y.: Academic Press 10.1016/j.virol.2005.09.030

Mani, Bernhard; Baltzer, Claudia; Valle, Noelia; Almendral, José; Kempf, Christoph; Ros, Carlos (2006). Low pH-dependent endosomal processing of the incoming parvovirus minute virus of mice virion leads to externalization of the VP1 N-terminal sequence (N-VP1), N-VP2 cleavage, and uncoating of the full-length genome. Journal of virology, 80(2), pp. 1015-1024. Baltimore: American Society for Microbiology 10.1128/JVI.80.2.1015-1024.2006

Ros, Carlos; Gerber, Marco; Kempf, Christoph (2006). Conformational changes in the VP1-unique region of native human parvovirus B19 lead to exposure of internal sequences that play a role in virus neutralization and infectivity. Journal of virology, 80(24), pp. 12017-12024. Baltimore: American Society for Microbiology 10.1128/JVI.01435-06

Ros, Carlos; Kempf, Christoph (2004). The ubiquitin-proteasome machinery is essential for nuclear translocation of incoming minute virus of mice. Virology, 324(2), pp. 350-360. Academic Press 10.1016/j.virol.2004.04.016

Ros, Carlos; Burckhardt, Christoph J; Kempf, Christoph (2002). Cytoplasmic trafficking of minute virus of mice: low-pH requirement, routing to late endosomes, and proteasome interaction. Journal of virology, 76(24), pp. 12634-12645. American Society for Microbiology 10.1128/JVI.76.24.12634-12645.2002

Ros, Carlos; Belák, Sándor (2002). Characterization of the glycoprotein B gene from ruminant alphaherpesviruses. Virus genes, 24(2), pp. 99-105. Nijhoff 10.1023/A:1014504730475

Conference or Workshop Item

Ros, Carlos (2017). Development of a relevant model virus system, cutthroat trout virus, for hepatitis E virus clearance studies (Unpublished). In: The principles of viral safety for biologicals and vaccines. Dubrovnik. 30 May-01 June 2017.