Prof. Dr. Sebastian Leidel Forschungsgruppenleiter Departement für Chemie, Biochemie und Pharmazie Telefon +41 31 684 42 96 Telefon2 +41 31 684 43 43 (Sekretariat) E-Mail sebastian.leidel@unibe.ch Büro N430 Postadresse Freiestrasse 3 CH - 3012 Bern
Lebenslauf Study 1991-2001: Undergraduate studies in Protestant Theology, University of Siegen, University of Marburg, Hebrew University Jerusalem and Heidelberg University 1996-2001: Diploma studies in Biology, Heidelberg University 2000-2001: Diploma Thesis with Hans Schöler at the University of Pennsylvania, Kennett Square (Topic: Induced Expression of Oct4 in Embryoid Bodies) 2001-2005: PhD Thesis with Pierre Gönczy at the Swiss Institute for Experimental Cancer Research, Lausanne (Topic: Centrosome duplication in Caenorhabditis elegans: The role of sas genes) Career 2005-2008: Postdoc with Matthias Peter, Institute of Biochemistry, ETH Zurich (Research topic: Functional characterization of the URM1-pathway) 2008-2010: Lecturer, Institute of Biochemistry, ETH Zurich (Research topic: tRNA modification by the URM1-pathway) 2010-2019: Max Planck Research Group Leader, Max Planck Institute for Molecular Biomedicine, Muenster, Germany (Research topics: The in-vivo function of RNA modifications in development and disease; Translational quality control) since August 2018: Full Professor of RNA Biochemistry at the Department of Chemistry and Biochemistry / Department of Chemistry, Biochemistry and Pharmaceutical Sciences (since January 2021), University of Bern Prizes and Awards 2012: ERC Starting Grant 2016: James Heineman Research Award for Outstanding Research Achievements
Forschungsschwerpunkt Virtually all cellular RNA molecules carry chemical modifications of their nucleotides. We know most of the enzymes responsible for these modifications. However, we still know little about their function and regulation during development and disease. In our group, we use different model organisms from yeast to zebrafish and human cell culture in combination with advanced methods like ribosome profiling or RNA mass spectrometry to tackle this question. Website of the research group
Publikationen For a full list of publications, please see: ORCID: orcid.org/0000-0002-0523-6325 Google Scholar ID: https://scholar.google.de/citations?user=cunKfWQAAAAJ&hl=de&oi=ao
Mitgliedschaften German Society for Biochemistry and Molecular Biology (since 2016) Cells-in-Motion Cluster of Excellence, University of Muenster (since 2015) Muenster Graduate School of Evolution, University of Muenster (since 2014) Young Academy of Europe (since 2013) - Elected Board Member and Treasurer RNA Society (since 2009) German Society for Cell Biology (DGZ) (since 1999) European Society for the Study of Science and Theology (ESSSAT) (since 1999)
