Departement für Chemie, Biochemie und Pharmazie

Lehre & Forschung

Links

Lebenslauf

  • 1979 – 1986: Studies in Biochemistry, University of Zürich.
    Diploma thesis on “Differential Chemical Modification of Cytochrome-c” in the lab of Prof. H.R. Bosshard​
  • 1986 – 1992: Awarded PhD Thesis in Chemistry at the University of Zürich:
    “Identification and Isolation of the Tocopherol-Cyclase of Anabaena-Variabilis Kützing” (supervisor Prof. W.-D. Woggon)
  • 1993 – 1996: Postdoctoral research at the Society for Biotechnological Research (GBF) Braunschweig, Germany.
    “Synthesis and crystallization of semi-synthetic D-amino acid oxidase for X-ray crystallography and biosensor applications”
  • 1996 – 2000: Postdoctoral research fellow at the Institute for Biochemistry and Molecular Biology, University of Bern.
    “In-vitro expression and characterization of human Tocopherol-binding proteins”
  • 2001 – 2003: Postdoctoral research fellow at the Department of Chemistry and Biochemistry, University of Bern.
    “Structure determination of human lipid-transfer proteins”
  • 2003 – 2006: Research group leader in the group of Prof. Peter Dimroth at the Institute of Microbiology, ETHZ.
    “Functional and structural investigations on the ATP-synthase of bacillus sp. TA2”
  • Since 2006: Lecturer and group leader at the Department of Chemistry and Biochemistry / Department of Chemistry, Biochemistry and Pharmaceutical Sciences (since 2021), University of Bern.
    “Structural and functional studies on lipid carriers associated with retinopathies and neurological disorders”
  • Since 2014: Associate professor in biochemistry at the University of Bern (Assoziierter Professor)

 

Forschungsschwerpunkt

Current Research Interests

Our goal is to understand the linkage between dysfunctional SEC14-like proteins and human diseases. In particular, we try to understand how members of the SEC14-like family of proteins recognize and shuttle specific lipids between compartments. Besides the biophysical aspects of targeted lipid-transfer we aim to understand how human retinopathies and neurological disorders are associated with missense mutations of the carriers.

Major research projects

  • Vitamin E retention and homeostasis
  • The role of Vitamin A binding proteins in the chemistry of vision
  • Modulation of cholesterol endosynthesis by SEC14-like proteins

Publikationen

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Journal Article

Personne, Hippolyte; Paschoud, Thierry; Fulgencio, Sofia; Baeriswyl, Stéphane; Köhler, Thilo; van Delden, Christian; Stocker, Achim; Javor, Sacha; Reymond, Jean-Louis (2023). To Fold or Not to Fold: Diastereomeric Optimization of an α-Helical Antimicrobial Peptide. Journal of medicinal chemistry, 66(11), pp. 7570-7583. American Chemical Society 10.1021/acs.jmedchem.3c00460

Baeriswyl, Stéphane; Personne, Hippolyte; Di Bonaventura, Ivan; Köhler, Thilo; van Delden, Christian; Stocker, Achim; Javor, Sacha; Reymond, Jean-Louis (2021). A mixed chirality α-helix in a stapled bicyclic and a linear antimicrobial peptide revealed by X-ray crystallography. RSC chemical biology, 2(6), pp. 1608-1617. Royal Society of Chemistry 10.1039/D1CB00124H

Aeschimann, Walter; Kammer, Stephan; Staats, Stefanie; Schneider, Petra; Schneider, Gisbert; Rimbach, Gerald; Cascella, Michele; Stocker, Achim (2021). Engineering of a functional γ-tocopherol transfer protein. Redox biology, 38, p. 101773. Elsevier 10.1016/j.redox.2020.101773

Baeriswyl, Stéphane; Gan, Bee Ha; Siriwardena, Thissa N.; Visini, Ricardo; Robadey, Maurane; Javor, Sacha; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2019). X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes. ACS Chemical Biology, 14(4), pp. 758-766. American Chemical Society 10.1021/acschembio.9b00047

Baeriswyl, Stéphane; Javor, Sacha; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2019). X‐Ray Crystal Structure of a Second‐Generation Peptide Dendrimer in Complex with Pseudomonas aeruginosa Lectin LecB. Helvetica chimica acta, 102(9) Wiley 10.1002/hlca.201900178

Bermúdez, Luisa; Del Pozo, Talía; Silvestre Lira, Bruno; de Godoy, Fabiana; Boos, Irene; Romanò, Cecilia; Previtali, Viola; Almeida, Juliana; Bréhélin, Claire; Asis, Ramón; Quadrana, Leandro; Demarco, Diego; Alseekh, Saleh; Salinas Gamboa, Rigel; Pérez-Flores, Laura; Dominguez, Pia Guadalupe; Rothan, Christophe; Fernie, Alisdair Robert; González, Maurício; Stocker, Achim; ... (2018). A Tomato Tocopherol-Binding Protein Sheds Light on Intracellular α-Tocopherol Metabolism in Plants. Plant & cell physiology, 59(11), pp. 2188-2203. Oxford Academic 10.1093/pcp/pcy191

Peltzer, Raphael Mathias; Kolli, Hima Bindu; Stocker, Achim; Cascella, Michele (2018). Self-Assembly of α-Tocopherol Transfer Protein Nanoparticles: A Patchy Protein Model. The Journal of Physical Chemistry B, 122(28), pp. 7066-7072. American Chemical Society 10.1021/acs.jpcb.8b05936

Aeschimann, Walter; Staats, Stefanie; Kammer, Stephan Martin; Olieric, Natacha; Jeckelmann, Jean-Marc; Fotiadis, Dimitrios José; Netscher, Thomas; Rimbach, Gerald; Cascella, Michele; Stocker, Achim (2017). Self-assembled α-Tocopherol Transfer Protein Nanoparticles Promote Vitamin E Delivery Across an Endothelial Barrier. Scientific Reports, 7(1) Nature Publishing Group 10.1038/s41598-017-05148-9

Di Bonaventura, Ivan; Jin, Xian; Visini, Ricardo; Probst, Daniel; Javor, Sacha; Gan, Bee-Ha; Michaud, Gaëlle; Natalello, Antonino; Doglia, Silvia Maria; Köhler, Thilo; van Delden, Christian; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2017). Chemical space guided discovery of antimicrobial bridged bicyclic peptides against Pseudomonas aeruginosa and its biofilms. Chemical Science, 8(10), pp. 6784-6798. The Royal Society of Chemistry 10.1039/C7SC01314K

He, Runze; Di Bonaventura, Ivan; Visini, Ricardo; Gan, Bee-Ha; Fu, Yongchun; Probst, Daniel; Lüscher, Alexandre; Köhler, Thilo; van Delden, Christian; Stocker, Achim; Hong, Wenjing; Darbre, Tamis; Reymond, Jean-Louis (2017). Design, crystal structure and atomic force microscopy study of thioether ligated d , l -cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa. Chemical Science, 8(11), pp. 7464-7475. The Royal Society of Chemistry 10.1039/C7SC01599B

Probst, Markus; Aeschimann, Walter; Chau, Thi T H; Langenegger, Simon Matthias; Stocker, Achim; Häner, Robert (2016). Structural insight into DNA-assembled oligochromophores: crystallographic analysis of pyrene- and phenanthrene-modified DNA in complex with BpuJI endonuclease. Nucleic acids research, 44(15), pp. 7079-7089. Information Retrieval Ltd. 10.1093/nar/gkw644

Röthlisberger, Pascal; Istrate, Alena; Marcaida Lopez, M. J.; Visini, Ricardo; Stocker, Achim; Reymond, Jean-Louis; Leumann, Christian (2016). X-ray structure of a lectin-bound DNA duplex containing an unnatural phenanthrenyl pair. Chemical communications, 52(26), pp. 4749-4752. Royal Society of Chemistry 10.1039/c6cc00374e

Michaud, Gaëlle; Visini, Ricardo; Bergman, Manfred Max; Salerno, Gianluca; Bosco, Rosa; Gillon, Emilie; Richichi, Barbara; Nativi, Cristina; Imberty, Anne; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2016). Overcoming antibiotic resistance in Pseudomonas aeruginosa biofilms using glycopeptide dendrimers. Chemical Science, 7(1), pp. 166-182. The Royal Society of Chemistry 10.1039/c5sc03635f

Bergman, Manfred Max; Michaud, Gaëlle; Visini, Ricardo; Jin, Xian; Gillon, Emilie; Stocker, Achim; Imberty, Anne; Darbre, Tamis; Reymond, Jean-Louis (2015). Multivalency effects in Pseudomonas aeruginosa biofilm inhibition and dispersal by glycopeptide dendrimers targeting lectin LecA. Organic & biomolecular chemistry, 14(1), pp. 138-148. Royal Society of Chemistry 10.1039/C5OB01682G

Wagner, Anika; Piegholdt, Stefanie; Rabe, Doerte; Baenas, Nieves; Schloesser, Anke; Eggersdorfer, Manfred; Stocker, Achim; Rimbach, Gerald (2015). Epigallocatechin gallate (EGCG) affects glucose metabolism and enhances fitness and life span in Drosophila melanogaster. OncoTarget, 6(31), pp. 30568-30578. Impact Journals LLC 10.18632/oncotarget.5215

Visini, Ricardo; Bergman, Manfred Max; Michaud, Gaelle; Pertici, Francesca; Fu, Ou; Pukin, Aliaksei; Branson, Thomas; Thies-Weesie, Dominique; Kemmink, Johan; Gillon, Emilie; Imberty, Anne; Stocker, Achim; Darbre, Tamis; Pieters, Roland; Reymond, Jean-Louis (2015). Structural Insight into Multivalent Galactoside Binding to Pseudomonas aeroginosa lectin LecA. ACS Chemical Biology, 10(11), pp. 2455-2462. American Chemical Society 10.1021/acschembio.5b00302

Lamprakis, Christos; Stocker, Achim; Cascella, Michele (2015). Mechanisms of recognition and binding of α-TTP to the plasma membrane by multi-scale molecular dynamics simulations. Frontiers in Molecular Biosciences, 2(36) Frontiers 10.3389/fmolb.2015.00036

Christen, Monika; Marcaida, Maria; Lamprakis, Christos; Aeschimann, Walter; Vaithilingam, Jathana; Schneider, Petra; Hilbert, Manuel; Schneider, Gisbert; Cascella, Michele; Stocker, Achim (2015). Evidence for direct squalene and 2,3-oxidosqualene binding by supernatant protein factor. Journal of structural biology, 190(190), pp. 261-270. Elsevier 10.1016/j.jsb.2015.05.001

Piegholdt, Stefanie; Pallauf, Kathrin; Esatbeyoglu, Tuba; Speck, Nancy; Reiss, Karina; Ruddigkeit, Lars; Stocker, Achim; Huebbe, Patricia; Rimbach, Gerald (2014). Biochanin A and prunetin improve epithelial barrier function in intestinal CaCo-2 cells via downregulation of ERK, NF-κB, and tyrosine phosphorylation. Free radical biology & medicine, 70, pp. 255-264. Elsevier 10.1016/j.freeradbiomed.2014.02.025

Bartoloni, Marco; Waltersperger, Sandro; Bumann, Mario; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2014). Stereoselective synthesis and structure determination of a bicyclo[3.3.2]decapeptide. Arkivoc, 2014(3), p. 113. Michigan Publishing 10.3998/ark.5550190.p008.500

Bolze, Christin Saskia; Helbling, Rachel; Owen, Robin L.; Pearson, Arwen R.; Pompidor, Guillaume; Dworkowski, Florian; Furrer, Julien; Golczak, Marcin; Fuchs, Martin; Palczewski, Krzysztof; Cascella, Michele; Stocker, Achim (2014). Human Cellular Retinaldehyde-Binding Protein Has Secondary Thermal 9- cis -Retinal Isomerase Activity. Journal of the American Chemical Society, 136(1), pp. 137-146. American Chemical Society 10.1021/ja411366w

Helbling, Rachel E.; Lamprakis, Christos; Aeschimann, Walter; Bolze, Cristin S.; Stocker, Achim; Cascella, Michele (2014). Mechanisms of Ligand–Protein Interaction in Sec-14-like Transporters Investigated by Computer Simulations. CHIMIA, 68(9), pp. 615-619. Bern: Schweizerische Chemische Gesellschaft 10.2533/chimia.2014.615

Kadam, Rameshwar U.; Bergman, Manfred Max; Garg, Divita; Gabrieli, Gabriele; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2013). Structure-Based Optimization of the Terminal Tripeptide in Glycopeptide Dendrimer Inhibitors of Pseudomonas aeruginosa Biofilms Targeting LecA. Chemistry - a European journal, 19(50), pp. 17054-17063. Wiley-VCH 10.1002/chem.201302587

Helbling, Rachel E.; Bolze, Christin Saskia; Golczak, Marcin; Palczewski, Krzysztof; Stocker, Achim; Cascella, Michele (2013). Cellular Retinaldehyde Binding Protein—Different Binding Modes and Micro-Solvation Patterns for High-Affinity 9- cis - and 11- cis -Retinal Substrates. Journal of physical chemistry - B, 117(37), pp. 10719-10729. American Chemical Society 10.1021/jp405410t

Kadam, Rameshwar U.; Garg, Divita; Schwartz, Julian; Visini, Ricardo; Sattler, Michael; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2013). CH−π “T-Shape” Interaction with Histidine Explains Binding of Aromatic Galactosides to Pseudomonas aeruginosa Lectin LecA. ACS Chemical Biology, 8(9), pp. 1925-1930. American Chemical Society 10.1021/cb400303w

Cascella, Michele; Bärfuss, Simon; Stocker, Achim (2013). Cis-retinoids and the chemistry of vision. Archives of biochemistry and biophysics, 539(2), pp. 187-195. Elsevier 10.1016/j.abb.2013.06.003

Helbling, Rachel E.; Aeschimann, Walter; Simona, Fabio; Stocker, Achim; Cascella, Michele (2012). Engineering Tocopherol Selectivity in alpha-TTP: A Combined In Vitro/In Silico Study. PLoS ONE, 7(11), e49195. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0049195

Kadam, Rameshwar U.; Bergman, Manfred Max; Hurley, Matthew; Garg, Divita; Cacciarini, Martina; Swiderska, Magdalena A.; Nativi, Cristina; Sattler, Michael; Smyth, Alan R.; Williams, Paul; Camara, Miguel; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2011). A Glycopeptide Dendrimer Inhibitor of the Galactose-Specific Lectin LecA and of Pseudomonas aeruginosa Biofilms. Angewandte Chemie (International ed.), 50(45), pp. 10631-10635. Weinheim: Wiley-VCH 10.1002/anie.201104342

Ernst, I. M.; Wagner, A. E.; Schuemann, C.; Storm, N.; Hoppner, W.; Doring, F.; Stocker, A.; Rimbach, G. (2011). Allyl-, butyl- and phenylethyl-isothiocyanate activate Nrf2 in cultured fibroblasts. Pharmacological research, 63(3), pp. 233-240. Oxford: Elsevier 10.1016/j.phrs.2010.11.005

He, Xiaoqin; Lobsiger, Joel; Stocker, Achim (2009). Bothnia dystrophy is caused by domino-like rearrangements in cellular retinaldehyde-binding protein mutant R234W. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 106(44), pp. 18545-18550. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.0907454106

Stocker, Achim; Keis, Stefanie; Vonck, Janet; Cook, Gregory; Dimroth, Peter (2007). The Structural Basis for Unidirectional Rotation of Thermoalkaliphilic F1-ATPase. Structure, 15(8), pp. 904-914. Cambridge, Mass.: Cell Press 10.1016/j.str.2007.06.009

Keis, Stefanie; Stocker, Achim; Dimroth, Peter; Cook, Gregory (2006). Inhibition of ATP hydrolysis by thermoalkaliphilic F1Fo-ATP synthase is controlled by the C terminus of the epsilon subunit. Journal of bacteriology, 188(11), pp. 3796-3804. Washington, D.C.: American Society for Microbiology 10.1128/JB.00040-06

Stocker, Achim; Keis, Stefanie; Cook, Gregory M; Dimroth, Peter (2005). Purification, crystallization, and properties of F1-ATPase complexes from the thermoalkaliphilic Bacillus sp. strain TA2.A1. Journal of structural biology, 152(2), pp. 140-145. Elsevier 10.1016/j.jsb.2005.08.005

Stocker, Achim (2004). Molecular mechanisms of vitamin E transport. Annals of the New York Academy of Sciences, 1031, pp. 44-59. Blackwell 10.1196/annals.1331.005

Morley, S; Panagabko, C; Stocker, Achim; Atkinson, J; Manor, D (2004). Structure-function relationship in the tocopherol transfer protein. Annals of the New York Academy of Sciences, 1031, pp. 332-333. Blackwell 10.1196/annals.1331.035

Morley, Samantha; Panagabko, Candace; Shineman, Diana; Mani, Bernhard; Stocker, Achim; Atkinson, Jeffrey; Manor, Danny (2004). Molecular determinants of heritable vitamin E deficiency. Biochemistry, 43(14), pp. 4143-4149. American Chemical Society 10.1021/bi0363073

Stocker, Achim; Baumann, Ulrich (2003). Supernatant protein factor in complex with RRR-alpha-tocopherylquinone: a link between oxidized Vitamin E and cholesterol biosynthesis. Journal of molecular biology, 332(4), pp. 759-765. Elsevier 10.1016/s0022-2836(03)00924-0

Meier, Reto; Tomizaki, Takashi; Schulze-Briese, Clemens; Baumann, Ulrich; Stocker, Achim (2003). The molecular basis of vitamin E retention: structure of human alpha-tocopherol transfer protein. Journal of molecular biology, 331(3), pp. 725-734. Elsevier 10.1016/s0022-2836(03)00724-1

Stocker, Achim; Tomizaki, Takashi; Schulze-Briese, Clemens; Baumann, Ulrich (2002). Crystal structure of the human supernatant protein factor. Structure, 10(11), pp. 1533-1540. Cell Press 10.1016/s0969-2126(02)00884-5

Azzi, A; Breyer, I; Feher, M; Ricciarelli, R; Stocker, Achim; Zimmer, S; Zingg, J (2001). Nonantioxidant functions of alpha-tocopherol in smooth muscle cells. Journal of nutrition, 131(2), 378S-81S. American Society for Nutrition 10.1093/jn/131.2.378S

Zimmer, S; Stocker, Achim; Sarbolouki, M N; Spycher, S E; Sassoon, J; Azzi, A (2000). A novel human tocopherol-associated protein: cloning, in vitro expression, and characterization. Journal of biological chemistry, 275(33), pp. 25672-25680. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M000851200

Azzi, A; Breyer, I; Feher, M; Pastori, M; Ricciarelli, R; Spycher, S; Staffieri, M; Stocker, Achim; Zimmer, S; Zingg, J M (2000). Specific cellular responses to alpha-tocopherol. Journal of nutrition, 130(7), pp. 1649-1652. American Society for Nutrition 10.1093/jn/130.7.1649

Azzi, Angelo; Stocker, Achim (2000). Vitamin E: non-antioxidant roles. Progress in lipid research, 39(3), pp. 231-255. Elsevier 10.1016/s0163-7827(00)00006-0

Stocker, Achim; Azzi, Angelo (2000). Tocopherol-binding proteins: their function and physiological significance. Antioxidants & redox signalling, 2(3), pp. 397-404. Mary Ann Liebert 10.1089/15230860050192170

Azzi, Angelo; Boscoboinik, Daniel; Clément, Sophie; Özer, Nesrin; Ricciarelli, Roberta; Stocker, Achim (1999). Vitamin E mediated response of smooth muscle cell to oxidant stress. Diabetes research and clinical practice, 45(2-3), pp. 191-198. Elsevier 10.1016/s0168-8227(99)00049-2

Negri, A; Buckmann, A F; Tedeschi, G; Stocker, Achim; Ceciliani, F; Treu, C; Ronchi, S (1999). Covalent flavinylation of L-aspartate oxidase from Escherichia coli using N6-(6-carboxyhexyl)-FAD succinimidoester. Journal of protein chemistry, 18(6), pp. 671-676. Springer 10.1023/a:1020606323716

Stocker, Achim; Zimmer, S; Spycher, S E; Azzi, A (1999). Identification of a novel cytosolic tocopherol-binding protein: structure, specificity, and tissue distribution. IUBMB Life, 48(1), pp. 49-55. Wiley 10.1080/713803478

Azzi, A; Boscoboinik, D; Clément, S; Ozer, N K; Ricciarelli, R; Stocker, Achim; Tasinato, A; Sirikçi, O (1997). Signalling functions of alpha-tocopherol in smooth muscle cells. International Journal for Vitamin and Nutrition Research, 67(5), pp. 343-349. Hogrefe

Stocker, Achim; Fretz, Heinz; Frick, Haroun; Rüttimann, August; Woggon, Wolf-Dietrich (1996). The substrate specificity of tocopherol cyclase. Bioorganic & medicinal chemistry, 4(7), pp. 1129-1134. Elsevier 10.1016/0968-0896(96)00125-3

Willner, Itamar; Blonder, Ron; Katz, Eugenii; Stocker, Achim; Bückmann, Andreas F. (1996). Reconstitution of Apo-Glucose Oxidase with a Nitrospiropyran-Modified FAD Cofactor Yields a Photoswitchable Biocatalyst for Amperometric Transduction of Recorded Optical Signals. Journal of the American Chemical Society, 118(22), pp. 5310-5311. American Chemical Society 10.1021/ja960228f

Sztajer, H.; Wang, W.; Lünsdorf, H.; Stocker, Achim; Schmid, R. D. (1996). Purification and some properties of a novel microbial lactate oxidase. Applied microbiology and biotechnology, 45(5), pp. 600-606. Springer 10.1007/s002530050736

Riklin, Azalla; Katz, Eugenii; Wiliner, Itamar; Stocker, Achim; Bückmann, Andreas F. (1995). Improving enzyme–electrode contacts by redox modification of cofactors. Nature, 376(6542), pp. 672-675. Macmillan Journals Ltd. 10.1038/376672a0

Matile, Stefan; Hansen, Thorsten; Stocker, Achim; Woggon, Wolf-Dietrich (1994). β ‐Cyclodextrin‐Mediated Regioselective Hydrolysis of 5,10,15,20‐tetrakis[2,4‐bis(pivaloyloxy)phenyl]‐21H,23H ‐porphine. Helvetica chimica acta, 77(4), pp. 1087-1098. Verlag Helvetica Chimica Acta 10.1002/hlca.19940770422

Stocker, Achim; Derungs, Giusep; Woggon, Wolf-Dietrich; Netscher, Thomas; Rüttimann, August; Müller, Robert K.; Schneider, Heinz; Todaro, Louis J. (1994). The Reaction Mechanism of Chromanol-Ring Formation Catalyzed by tocopherol cyclase from Anabaena variabilis KÜTZING (Cyanobacteria). Helvetica chimica acta, 77(7), pp. 1721-1737. Verlag Helvetica Chimica Acta 10.1002/hlca.19940770705

Stocker, Achim; Woggon, Wolf-Dietrich; Rüttimann, August (1993). Identification of The Tocopherol-Cyclase in the Blue-Green Algae Anabaena variabilis KÜTZING (Cyanobacteria). Helvetica chimica acta, 76(4), pp. 1729-1738. Verlag Helvetica Chimica Acta 10.1002/hlca.19930760429

Book Section

He, Xiaoqin; Lobsiger, Joel; Stocker, Achim (2012). Molecular Clues to Bothnia-Type Retinal Dystrophy. In: LaVail, Matthew M.; Ash, John D.; Anderson, Robert E.; Hollyfield, Joe G.; Grimm, Christian (eds.) Retinal Degenerative Diseases. Advances in Experimental Medicine and Biology: Vol. 723 (pp. 589-594). Heidelberg: Springer Verlag 10.1007/978-1-4614-0631-0_75

Özer, Nesrin K.; Taha, Suzan; Stocker, Achim; Azzi, Angelo (1999). Effects of High Cholesterol, Vitamin E, and Probucol on Protein Kinase C Activity and Proliferation of Smooth Muscle Cells. In: Antioxidant Food Supplements in Human Health (pp. 73-86). Elsevier 10.1016/B978-012543590-1/50006-8

Özer, Nesrin K.; Sirikci, Önder; Taha, Suzan; Engin, N. Kaya; Boscoboinik, Daniel; Clément, Sophie; Stocker, Achim; Azzi, Angelo (1998). Prevention of Atherosclerosis by α-Tocopherol in Smooth Muscle Cells by a Mechanism Involving Signal Transduction Modulation. In: Free Radicals, Oxidative Stress, and Antioxidants (pp. 333-342). Springer 10.1007/978-1-4757-2907-8_29

Bückmann, Andreas F.; Wray, Victor; Stocker, Achim (1997). [33] Synthesis of N6-(2-aminoethyl)-FAD, N6-(6-carboxyhexyl)-FAD, and related compounds. In: McCormick, Donald B.; Suttie, John W.; Wagner, Conrad (eds.) Vitamins and Coenzymes Part J. Methods in Enzymology: Vol. 280 (pp. 360-374). Elsevier 10.1016/s0076-6879(97)80127-9

Conference or Workshop Item

Personne, Hippolyte Jean-Claude René; Baeriswyl, Stéphane; Stocker, Achim; Javor, Sacha; Reymond, Jean-Louis (25 August 2020). X-Ray Crystallographic Studies of Short Antimicrobial Helical Peptides against Multidrug Resistant Gram-Negative Bacteria (Unpublished). In: SCS Fall meeting 2020. University of Bern. 25th August 2020.

Aeschimann, Walter; Staats, Stefanie; Kammer, Stephan Martin; Olieric, Natacha; Jeckelmann, Jean-Marc; Fotiadis, Dimitrios José; Netscher, Thomas; Rimbach, Gerald; Cascella, Michele; Stocker, Achim (2017). Self-assembled α-Tocopherol Transfer Protein Nanoparticles Promote Vitamin E Delivery Across an Endothelial Barrier (Unpublished). In: 52nd Bürgenstock Conference. Brunnen, Switzerland. 30th of April to 4th of May.

Stocker, Achim (7 November 2016). Homeostasis of α-Tocopherol and of 11-cis-Retinal is Regulated by Proteins of the Sec14 Superfamily (Unpublished). In: Seminar. Institute of Human Nutrition and Food Science, Christian-Albrechts-University, Kiel, Germany. 07.11.2016.

Stocker, Achim (2012). Combined X-ray crystallographic, in situ UV-Vis and QM/MM studies highlight alternate retinal binding modes in CRALBP (Unpublished). In: Presentation given at the 15th International Conference on Retinal Proteins. Ascona, Switzerland. 30.9.2012.

Patent

Achim Stocker (2017). Nanospheres of sec14-like proteins and cognate ligands (PCT/EP2017/051,409)

Mitgliedschaften

  • Berner Chemische Gesellschaft (BCG)
  • Biochemische Vereinigung Bern (BVB)